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KMID : 0367219860030010003
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Sejong Medical Journal
1986 Volume.3 No. 1 p.3 ~ p.7
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The Significance of the Measurement of Immunosuppressive Acid Protein(IAP) Level in Cancer Patients after Curative Surgery
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최윤백/Choi, Youn-Baik
김정택/김진복/정성은/Kim, Jung-Taek/Kim, Jin-Pok/Jung, Sung-Eun
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Abstract
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To evaluate the significance and the relaticnship between serum IAP level and the postoperative progression of the cancer, we measured IAP level in 42 gastric cancer patients, 11 colorectal cancer patients, and 12 breast cancer patients 2 years after curative surgery was performed as well as the preoperative IAP level of 54 stomach cancer patients, 28 colorectal cancer patients, and 24 breast cancer patients.
1) IAP level in preoperative gastric cancer patients was 596.2 210.5 glml, 51.8% positive rate, and in postoperative patients, 352.8 67.3 g/ml, 0% positive rate.
2) In preoperative colorectal cancer patients, lAP level was 519.8 195.2 g/ml, 50.0% positive rate, and in postoperative patients 401.2 140.3 g/ml, 9.1% positive rate.
3) In preoperative breast cancer patients, IAP level was 499.6 170.3 g/ml, 45.8% positive rate and in postoperative patients, 365.0 20.6 g/ml, 0% positive rate.
4) The change of IAP level as well as DNCB and T-cell count showed positive correlation with progression and surgical treatment in gastric cancer.
We concluded that the measurement of serum IAP level in cancer patients is an useful tool as an immune parameter study for the postoperative progression of the cancer.
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